SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Vitamin C (as L-ascorbic acid)
1,000  mg
1,111%

Top Medical Research Studies

9
Vitamin C alleviates cold sores
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
Direct effectiveness evaluation noted
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.

Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.

Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.

In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
Vitamin C shows potential for cold sores
A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus.
Combination treatment lacks isolation
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.

Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.

Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.

Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
Potential effects on cold sores
The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis.
Moderate relevance of findings
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.

The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.

Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More

Most Useful Reviews

10
Cold sores prevented
I haven’t caught a cold since using this product. My immunity has significantly improved.
Read More
9.5
Immune system boost
Vitamin C-1000 is renowned for its powerful antioxidant properties. It enhances immunity and protects against free radicals. I've found that during cold and flu season, taking one capsule daily at the first signs of illness helps prevent the onset of colds. This vitamin is crucial for boosting infection resistance and aids in collagen synthesis, as well as the absorption of other vital nutrients like vitamin E and iron. Additionally, it’s particularly important for anyone dealing with cold sores.
Read More
3.5
Not effective
I found this vitamin not very effective in managing the cold.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
  • All Researches
9
Vitamin C alleviates cold sores
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
Direct effectiveness evaluation noted
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.

Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.

Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.

In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
Vitamin C shows potential for cold sores
A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus.
Combination treatment lacks isolation
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.

Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.

Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.

Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
Potential effects on cold sores
The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis.
Moderate relevance of findings
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.

The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.

Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Cold sores prevented
I haven’t caught a cold since using this product. My immunity has significantly improved.
9.5
Immune system boost
Vitamin C-1000 is renowned for its powerful antioxidant properties. It enhances immunity and protects against free radicals. I've found that during cold and flu season, taking one capsule daily at the first signs of illness helps prevent the onset of colds. This vitamin is crucial for boosting infection resistance and aids in collagen synthesis, as well as the absorption of other vital nutrients like vitamin E and iron. Additionally, it’s particularly important for anyone dealing with cold sores.
Read More
3.5
Not effective
I found this vitamin not very effective in managing the cold.
8.8
Rarely sick now
I've taken this vitamin for over two years, initially purchasing it in Ukraine before discovering it cheaper on iHerb. Since starting, my immunity has improved significantly; I rarely fall ill, maybe just once a year with a cold. When I sense illness coming on, I increase my dosage to 1000-1500 mg daily, taking 500 mg regularly. The tablets are convenient to divide, ensuring my husband and I have enough for a long time. It's essential for anyone prone to cold sores.
Read More

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